Case Report


Granulicatella adiacens—A rare and challenging cause of endocarditis

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1 Infectious Diseases Department, Hospital Egas Moniz, Centro Hospitalar Lisboa Ocidental, Lisboa, Portugal

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Joana Patrícia Faitão Vasconcelos

Rua da Junqueira, 126, 1349-019 Lisboa,

Portugal

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Article ID: 100011Z16JV2021

doi: 10.5348/100011Z16JV2021CR

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How to cite this article

Vasconcelos JPF, Casanova S, Domingos J, Granado J, Baptista T, Mansinho K. Granulicatella adiacens—A rare and challenging cause of endocarditis. J Case Rep Images Infect Dis 2021;4:100011Z16JV2021.

ABSTRACT


Introduction: Infective endocarditis (IE) is a relatively rare but serious infection, inevitably fatal without treatment. Despite advances, its management is still challenging and often individualized. High-risk patients should be opportunely identified based on patients’ characteristics, cardiac or extracardiac complications, and the culprit infectious organism. Granulicatella adiacens, an oral commensal, is an increasingly recognized cause of IE, being a particularly virulent organism, associated to severe complications and an exceptionally challenging diagnosis and treatment.

Case Report: We report a case of G. adiacens IE in a previously healthy and immunocompetent patient, whose only risk factor was a known mild mitral regurgitation. He presented with a large and mobile vegetation, cardiac failure associated to structural cardiac damage, and silent embolic phenomena. Surgical intervention was early considered and mitral valve repair done after 7 days of directed antibiotic therapy.

Conclusion: This case emphasizes a rare, difficult to diagnose, and serious cause of IE that should be actively reminded.

Keywords: Bacterial endocarditis, Granulicatella adiacens, Heart valves

SUPPORTING INFORMATION


Author Contributions

Joana Patrícia Faitão Vasconcelos - Substantial contributions to conception and design, Acquisition of data, Drafting the article, Final approval of the version to be published

Sara Casanova - Substantial contributions to conception and design, Drafting the article, Final approval of the version to be published

João Domingos - Substantial contributions to conception and design, Revising it critically for important intellectual content, Final approval of the version to be published

Joana Granado - Substantial contributions to conception and design, Revising it critically for important intellectual content, Final approval of the version to be published

Teresa Baptista - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published

Kamal Mansinho - Substantial contributions to conception and design, Revising it critically for important intellectual content, Final approval of the version to be published

Guaranter of Submission

The corresponding author is the guarantor of submission.

Source of Support

None

Consent Statement

Written informed consent was obtained from the patient for publication of this article.

Data Availability

All relevant data are within the paper and its Supporting Information files.

Conflict of Interest

Authors declare no conflict of interest.

Copyright

© 2021 Joana Vasconcelos et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.