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Case Report
Brucella endocarditis of a prosthetic valve in a non-endemic region
1 MD, Laboratory for Medical Microbiology and Immunology, Elisabeth-TweeSteden Hospital, Tilburg, The Netherlands
2 MD, Department of Internal Medicine, Elisabeth-TweeSteden Hospital, Tilburg, The Netherlands
3 MD, PhD, Department of Anaesthesiology, Intensive Care and Pain Medicine, Catharina Hospital, Eindhoven, The Netherlands
4 MD, PhD, Laboratory for Medical Microbiology and Immunology, Elisabeth-TweeSteden Hospital, Tilburg, The Netherlands
Address correspondence to:
Rik van den Biggelaar
P.O. Box 747, 5000 AS, Tilburg,
The Netherlands
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Article ID: 100006Z16RB2020
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How to cite this article
van den Biggelaar R, Berrevoets MAH, Buise MP, Buiting AG. Brucella endocarditis of a prosthetic valve in a non-endemic region. J Case Rep Images Infect Dis 2020;3:100006Z16RB2020.ABSTRACT
Introduction: Brucellosis is a common bacterial zoonosis in endemic regions. Most cases of human disease are caused by contact with infected animals or consumption of contaminated animal products. In the Netherlands brucellosis in livestock had been eradicated so human disease is especially rare.
Case Report: We present a case of a 58-year-old female with a prosthetic valve endocarditis caused by Brucella melitensis. The patient had immigrated from an endemic region 12 months prior. She was treated with antibiotic triple therapy and valve replacement. The postoperative was complicated by multiple organ failure resulting in death.
Conclusion: Brucellosis has a wide spectrum of clinical manifestations and is poorly recognized in non-endemic regions. It should be considered in febrile patients whom had possible exposure at least up to a year prior. Delay of appropriate treatment could lead to potential life-threatening complications.
Keywords: Brucella melitensis, Brucellosis, Endocarditis, Prosthetic valve
SUPPORTING INFORMATION
Acknowledgments
We thank Wally Wonnink-de Jonge for providing the echocardiography image and Frans Reubsaet for the Brucella confirmation and biotyping data.
Author ContributionsRik van den Biggelaar - Substantial contributions to conception and design, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Marvin AH Berrevoets - Acquisition of data, Revising it critically for important intellectual content, Final approval of the version to be published
Marc P Buise - Acquisition of data, Revising it critically for important intellectual content, Final approval of the version to be published
Anton G Buiting - Revising it critically for important intellectual content, Final approval of the version to be published
Guaranter of SubmissionThe corresponding author is the guarantor of submission.
Source of SupportNone
Consent StatementWritten informed consent was obtained from the patient for publication of this article.
Data AvailabilityAll relevant data are within the paper and its Supporting Information files.
Conflict of InterestAuthors declare no conflict of interest.
Copyright© 2020 Rik van den Biggelaar et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.
